Thymulin studies and sources
Where can you check the thymulin studies?
Lab teams made thymulin to study immune cells. Each numbered note leads to the paper behind that study.
How do you use this thymulin source list?
A numbered mark beside a thymulin finding leads to the same number below; for example, [1] leads to the first study and [2] to the second. Each entry names the team, the date, and where the paper can be read.
Much of the basic work comes from the 1980s and 1990s. Later entries cover mouse studies and gene treatment. Entry 15 is useful only for telling thymalin from thymulin. Thymalin is a mix from a cow thymus, and the paper studied thymalin rather than thymulin. It can't support a claim that thymulin helps people.
- Dardenne M, Pléau JM, Nabarra B, Lefrancier P, Derrien M, Choay J, Bach JF. Contribution of zinc and other metals to the biological activity of the serum thymic factor. Proc Natl Acad Sci U S A. 1982;79(17):5370-3. ↗
- Dardenne M, Pleau JM. Interactions between zinc and thymulin. Met Based Drugs. 1994;1(2-3):233-9. ↗
- Bach JF, Dardenne M. Thymulin, a zinc-dependent hormone. Med Oncol Tumor Pharmacother. 1989;6(1):25-9. ↗
- Dardenne M, Savino W, Berrih S, Bach JF. A zinc-dependent epitope on the molecule of thymulin, a thymic hormone. Proc Natl Acad Sci U S A. 1985;82(20):7035-8. ↗
- Prasad AS, Meftah S, Abdallah J, Kaplan J, Brewer GJ, Bach JF, Dardenne M. Serum thymulin in human zinc deficiency. J Clin Invest. 1988;82(4):1202-10. ↗
- Incefy GS, Mertelsmann R, Yata K, Dardenne M, Bach JF, Good RA. Induction of differentiation in human marrow T cell precursors by the synthetic serum thymic factor, FTS. Clin Exp Immunol. 1980;40(2):396-406. ↗
- Pléau JM, Fuentes V, Morgat JL, Bach JF. Specific receptors for the serum thymic factor (FTS) in lymphoblastoid cultured cell lines. Proc Natl Acad Sci U S A. 1980;77(5):2861-5. ↗
- Parent G, Chevalier P, Zalles L, Sevilla R, Bustos M, Dhenin JM, Jambon B. In vitro lymphocyte-differentiating effects of thymulin (Zn-FTS) on lymphocyte subpopulations of severely malnourished children. Am J Clin Nutr. 1994;60(2):274-8. ↗
- Mocchegiani E, Ciavattini A, Santarelli L, Tibaldi A, Muzzioli M, Bonazzi P, Giacconi R, Fabris N. Role of zinc and alpha2 macroglobulin on thymic endocrine activity and on peripheral immune efficiency (natural killer activity and interleukin 2) in cervical carcinoma. Br J Cancer. 1999;79(2):244-50. ↗
- Hadley AJ, Rantle CM, Buckingham JC. Thymulin stimulates corticotrophin release and cyclic nucleotide formation in the rat anterior pituitary gland. Neuroimmunomodulation. 1997;4(2):62-9. ↗
- Reggiani PC, Morel GR, Cónsole GM, Barbeito CG, Rodriguez SS, Brown OA, Bellini MJ, Pléau JM, Dardenne M, Goya RG. The thymus-neuroendocrine axis: physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin. Ann N Y Acad Sci. 2009;1153:98-106. ↗
- Reggiani PC, Schwerdt JI, Console GM, Roggero EA, Dardenne M, Goya RG. Physiology and therapeutic potential of the thymic peptide thymulin. Curr Pharm Des. 2014;20(29):4690-6. ↗
- Novoselova EG, Khrenov MO, Glushkova OV, Lunin SM, Parfenyuk SB, Novoselova TV, Fesenko EE. Anti-inflammatory effects of IKK inhibitor XII, thymulin, and fat-soluble antioxidants in LPS-treated mice. Mediators Inflamm. 2014;2014:724838. ↗
- da Silva AL, de Oliveira GP, Kim N, Cruz FF, Kitoko JZ, Blanco NG, Martini SV, Hanes J, Rocco PRM, Suk JS, Morales MM. Nanoparticle-based thymulin gene therapy therapeutically reverses key pathology of experimental allergic asthma. Sci Adv. 2020;6(24):eaay7973. ↗
- Khavinson VKh, Morozov VG. Peptides of pineal gland and thymus prolong human life. Neuro Endocrinol Lett. 2003;24(3-4):233-40. (Context: thymalin, a bovine thymic complex distinct from thymulin.) ↗